LANDMARK STUDY SHOWS HALF OF CANCER PATIENTS ARE KILLED BY CHEMO — NOT CANCER

No matter how much doctors push the treatment, chemotherapy might not be the best option in the fight against cancer, as a new study shows up to 50 percent of patients are killed by the drugs — not the disease, itself.

Researchers from Public Health England and Cancer Research UK performed a groundbreaking study examining for the first time the numbers of cancer patients who died within 30 days of beginning chemotherapy — indicating the treatment, not the cancer, was the cause of death.

Looking at those death rates in hospitals across the U.K., researchers found an alarming mortality rate associated with chemotherapy.

Across “England around 8.4 per cent of patients with lung cancer, and 2.4 per cent of breast cancer patients died within a month,” the Telegraph reported.

“But in some hospitals the figure was far higher. In Milton Keynes the death rate for lung cancer treatment was 50.9 per cent, although it was based on a very small number of patients.”

Alarmingly, the one-month mortality rate at Lancashire Teaching Hospitals for those undergoing palliative, rather than curative, chemotherapy for lung cancer was a full 28 percent. One in five breast cancer patients receiving palliative care at Cambridge University Hospitals died from treatment.

In certain areas — Blackpool, Coventry, Derby, South Tyneside, and Surrey and Sussex — deaths of lung cancer patients by chemotherapy were ‘far higher’ than the national average.

Dr. Jem Rashbass, Cancer Lead for Public Health England — the national health care service, which requested the study — said, as quoted by the Telegraph:

“Chemotherapy is a vital part of cancer treatment and is a large reason behind the improved survival rates over the last four decades.

“However, it is powerful medication with significant side effects and often getting the balance right on which patients to treat aggressively can be hard.

“Those hospitals whose death rates are outside the expected range have had the findings shared with them and we have asked them to review their practice and data.”

For the analysis, researchers “included all women with breast cancer and all men and women with lung cancer residing in England, who were 24 years or older and who started a cycle” of chemotherapy in 2014.

Long the mainstay for treating various cancers, chemotherapy has finally drawn criticism in recent years, as the medicine does not differentiate between healthy and cancerous cells. Now, this study — published in the Lancet — shows how that powerful cell-destroying property can mean the demise for patients as well.

Researchers have advised physicians to exercise more caution in vetting which patients should ideally receive chemotherapy. Older and more infirm patients, in particular, might be better off without receiving palliative care, which is designed to offer relief instead of curing the disease.

“The statistics don’t suggest bad practice overall but there are some outliers,” noted Professor David Dodwell of the Institute of Oncology at St. James Hospital in Leeds.

“It could be data problems, and figures skewed because of just a few deaths, but nevertheless it could also be down to problems with clinical practice,” he continued.



“I think it’s important to make patients aware that there are potentially life threatening downsides to chemotherapy. And doctors should be more careful about who they treat with chemotherapy.”

All hospitals involved said they reviewed the information and remain certain chemotherapy is safe — with the caveat patient selection for the treatment may need to be more discretionary.

Professor David Cameron of the Edinburgh Cancer Centre at West General Hospital in Edinburgh, Scotland, noted, “The concern is that with some of the patients dying within 30 days of being given chemo probably shouldn’t have been given the chemo. But how many? There is no easy way to answer that, but perhaps looking at those places/hospitals where the death rate was higher might help.

“Furthermore, if we give less chemo then some patients will die because they didn’t get chemo. It’s a fine balance and the more data we have the better we can be at making sure we get the balance right.”

Meanwhile, doctors in the United States should probably take note, considering the sheer number of patients forced to undergo chemotherapy at the State’s behest despite objections from those patients and their families.

In one example, a 17-year-old diagnosed with Hodgkin lymphoma decided to seek alternatives to chemotherapy, but her doctors — so inculcated in state and Big Pharma propaganda — contacted family services, who then kidnapped the young adult and placed her in foster care.

She was finally allowed to return home once she agreed to undergo the often debilitating treatment — but ran away once doctors informed her she’d have to endure surgery for the implantation of a chemo port. In an incredible act of Orwellian Big Government, the Supreme Court ruled the State was in the right in this case — and after being kidnapped and forced into treatment against her will, was denied contact with her own family.

As unfathomably invasive as that was, it isn’t isolated.

Alternative treatments do, in fact, exist — the most promising among them for many cancers are various formulations of CBD oil, a cannabis derivative. But, thanks to the phenomenally failed war on drugs, cancer patients in most areas of the U.S. are unable to procure much needed medicine or are forced to receive treatment on the sly — risking time behind bars simply for wanting to cure themselves.


from : Landmark 

Why you need take Resveratrol?

• Resveratrol may reduce bad cholesterol  
• Resveratrol may prevent blood clots 

Dr. Isadore Rosenfeld, a media-savvy New York physician who dispensed medical advice in best-selling books, in magazine articles and on television, died on Jan. 30, 2018 in Greenwich, Conn. He was 91.

#resveratrol  #cancer #diabetes #heartdisease #stroke 
 

4 Powerful Health Benefits of Resveratrol

4 Powerful Health Benefits of Resveratrol

Scientists have been astonished by the remarkable health benefits associated with resveratrol.  This unique nutrient found in grape skins has a powerful effect on the genetic expression of the mitochondria within every cell.  By positively effecting mitochondrial function, resveratrol, has been shown to help in the prevention of cancer, heart disease and other metabolic conditions (1).  In this article, you will discover 4 powerful health benefits of resveratrol.

Researchers have been intrigued for years about what has been traditionally called the French paradox.  This refers to how many of these native French are able to smoke cigarettes and drink lots of alcohol and still maintain good health.  They have looked at the dark, fermented wines these individuals drink on a regular basis.
They have found the active compound in red wine, called resveratrol, has extraordinary health benefits.    Resveratrol is a unique polyphenolic anti-oxidant found in the grape skins and seeds and some berries.  It plays a critical role in the plant’s natural defense system against injury, infection and disease (2).

Resveratrol and Gene Expression:
Resveratrol has been shown to have an incredible influence on gene expression that has profound anti-aging effects (3).  This mimics the positive benefits of caloric restriction and extends lifespan.  Most people are intimidated by extreme caloric restriction and would prefer to get the same anti-aging benefits from an anti-oxidant rich diet and supplements such as resveratrol.
A Harvard study in 2003 found that resveratrol boosted the life span of yeast cells by as much as 70% (4).  They then carried the testing out with similar results in roundworms and fruit flies.  This made resveratrol the first compound to have anti-aging benefits in a widely divergent species.  Italian scientists in 2006 showed that resveratrol could extend life by more than 50% in more advanced species of fish (5).

Resveratrol and Mitochondrial Health:

Resveratrol has been shown to activate a group of mitochondrial proteins in the sirtuin family and in particular (SIRT1) (6).   Several studies have shown that this sirtuin activation results in an increased level of mitochrondria in the body.  This plays a big role in energy production, fat and sugar metabolism and blood sugar stability.  With improved blood sugar the body is better able to regulate insulin and other hormones which reduces inflammation and improves fat burning.
The mitochondria of the cell control the metabolic function of the cell and ultimately the body.  Resveratrol’s ability to reduce inflammatory stress on the mitochondria and upregulate mitochondrial numbers has an enormous impact on whole body health.  Healthy restored mitochondria are significantly more efficient and produce less free radicals than older mitochondria.

Resveratrol and the Nitric Oxide Cycle

Resveratrol has a strong ability at optimizing the health of the nitric oxide cycle.  Nitric oxide is a chemical signaling molecule that is involved in the nervous, immune and vascular systems.  There are three main forms of nitric oxide which include endothelial nitric oxide (eNOS), inducible nitric oxide (iNOS) and neuronal nitric oxide (nNOS).
Healthy brain and cardiovascular function depends upon a greater eNOS and nNOS activity and suppressed iNOS activity.  This pattern allows for healthy blood flow in the brain and coronary arteries and blood vessels throughout the body.
Chronic inflammatory stress lowers eNOS and nNOS activity and increases iNOS activity.  This pattern is a major risk factor for hypertenstion, cardiovascular disease and neurodegenerative states.
Resveratrol has been shown to strongly improve this nitric oxide cycle which enhances endothelial activity to enhance blood flow dynamics to important regions of the body such as the coronary arteries and brain (7, 8).  This strongly reduces the risk of heart disease and neurodegenerative states like Alzheimer’s and Parkinson’s.

Resveratrol and Cancer:

Resveratrol has a profound effect at inhibiting the master inflammatory compound Nuclear factor Kappa Beta (NF-KB) (9).  NF-KB initiates inflammatory processes that are implicated in cancer cell formation.  Resveratrol also makes cancer cells more vulnerable to our bodies natural immune cell induced attacks.  Scientists are looking very closely at reseveratrol as an adjunct therapy for increasing the effectiveness of traditional chemotherapy on destroying cancerous growths.
Cancer cells are known to have dysfunctional mitochondrial function.  This is evidenced in the inability for cancer cells to derive energy from oxidative phosphorylation.  These cells rely completely on anaerobic glycolysis for energy production.  Addressing the mitochondria which drives the energy production of the cell is key to terminating abnormal tissue growths
Part of the process of breast cancer is a dysregulation of the Heregulin-Beta1 (HRG-beta 1) cell signaling pathway.  This pathway activates the Matrix metalloproteinase (MMP) 9 enzyme which leads to invasive tumor growth. Resveratrol has also been able to shown to down regulate this pathway and slow the growth of breast cancer.
Many other studies have indicated resveratrol’s effectiveness in shutting down growth in pancreatic, liver, colon, prostatic, skin and many other cancer cell types (10, 11).  Most scientists relate this back to the ability of resveratrol to effect mitochondrial function through the sirtuin proteins that regulate proper function.

Proper Resveratrol Dosages:

Supplements should be in the range of 20-100 mg to achieve the same benefits observed in most of these studies on degenerative disease states.  The dosage of 20mg daily is appropriate for healthy adults without any significant health history to obtain the beneficial anti-aging gene expression that resveratrol provides.  Individuals with advanced cancer should look at getting dosages in the 100-200 mg range.
An ounce of red wine averages around 90 micrograms of resveratrol.  This is the 220 times less than the minimal dosage (20 mg) of resveratrol supplementation.  A glass of wine is approximately five and a third ounces.  At this scale it would take 41 glasses of red wine to achieve the minimal supplemental dosage of resveratrol used in these studies.

Resveratrol on 60 Minutes

Seventeen years ago, 60 Minutes first examined the French paradox, which suggested that despite a high fat diet and high consumption of wine, the French had a remarkably low incidence of heart disease, compared with Americans. Most researchers agreed that there was something in the wine that offered protection, and a few years later, even the highly cautious federal dietary guidelines say that red wine can be beneficial in moderation.

Today, scientists across the country have identified a substance in red wine called resveratrol that they believe might do more than just protect the heart, but could, in very high concentrations, significantly extend life by preventing a number of age-related illnesses. If they're right, we all may soon be taking a pill that could give us an extra decade or two of healthy old age.

Resveratrol on 60 Minutes.