Sunday, December 27, 2015

Sunday, December 6, 2015

The science of stem cells

The science of stem cells

Dr. Nathan Newman, a world-renowned dermatologist and cosmetic surgeon, began searching for a topical treatment to help patients recovering from burns and severe injuries. Knowing that stem cells drive cell growth and regeneration, he isolated the stem cell growth factors that serve as the “language” communicating cellular activity. Although other scientists were using plant-based growth factors, Dr. Newman derived his growth factors from the stem cells of healthy adults, theorizing that cell communication in the same “language” would be more effective.



Today, with the Executive Order I am about to sign, we will bring the change that so many scientists and researchers; doctors and innovators; patients and loved ones have hoped for, and fought for, these past eight years: we will lift the ban on federal funding for promising embryonic stem cell research. We will vigorously support scientists who pursue this research. And we will aim for America to lead the world in the discoveries it one day may yield. At this moment, the full promise of stem cell research remains unknown, and it should not be overstated. But scientists believe these tiny cells may have the potential to help us understand, and possibly cure, some of our most devastating diseases and conditions. To regenerate a severed spinal cord and lift someone from a wheelchair. To spur insulin production and spare a child from a lifetime of needles. To treat Parkinson‘s, cancer, heart disease and others that affect millions of Americans and the people who love them.

What are adult stem cells?

What are adult stem cells?


Promote new cell growth

New cell growth is an essential part of life—it’s how we grow from child to adult. But as we age and our growing decelerates, so does the production of new cells. At the same time, our body’s cells themselves age and their functions begin to slow. When it comes to your skin, this can lead to a dull, sagging complexion on the outside and cells that can’t efficiently accept nutrients and remove toxins on the inside

Jeunesse Global has introduced the first two anti aging products based on this amazing adult stem cells technology.

Adult cells are undifferentiated cells found throughout the body that divide to replenish dying cells and regenerate damaged tissues.

Also known as somatic stem cells, they can be found in children, as well as adults. Research into adult stem cells has been fueled by their abilities to divide or self-renew indefinitely and generate all the cell types of the organ from which they originate – potentially regenerating the entire organ from a few cells.

Adult stem cell technology is dramatically expanding the horizons of skin care development. This revolution in the science of youth is made possible because of the intersection of bio-engineering technology and years of product formulation expertise.

The greatest abundance of stem cells in the body is in adipose (fat) tissue. In a hypoallergenic process, the stem cells are extracted from the adipose tissue and cultured in a nutrient-rich media which becomes infused with the characteristics of the stem cells.

  Then extracted from the media using a sophisticated filtration process, leaving behind the actual stem cells

This stem cell media is then formulated with other state-of-the-art ingredients to create a “one of a kind” anti-aging facial serum, LUMINESCE™ cellular rejuvenation serum.

 This serum has been formulated with regulatory proteins, cytokines and interleukins, which replicate those same elements in the human body. Since these proteins have the same attributes, whether in the body or in this serum, there is a perfect interaction between this extraordinary product and natural body processes.

 The stem cell technology delivers more than 200 growth factors already found in natural skin. These growth factors and cytokines enter the pores of the skin then penetrate the epidermal barrier. The benefits are:

• restore your natural youthful luminosity, firmness, smoothness and elasticity of your skin.
• diminish the appearance of fine lines and wrinkles.

Check these videos about the Stem Cell.


 
 
 
 
 
 

How Much Can Human Life Span Be Extended?

How Much Can Human Life Span Be Extended?


Figure
When Jeanne Calment died in a nursing home in southern France in 1997, she was 122 years old, the longest-living human ever documented. But Calment's uncommon status will fade in subsequent decades if the predictions of some biologists and demographers come true. Life-span extension in species from yeast to mice and extrapolation from life expectancy trends in humans have convinced a swath of scientists that humans will routinely coast beyond 100 or 110 years of age. (Today, 1 in 10,000 people in industrialized countries hold centenarian status.) Others say human life span may be far more limited. The elasticity found in other species might not apply to us. Furthermore, testing life-extension treatments in humans may be nearly impossible for practical and ethical reasons.

Some of these effects may not occur in other species. A worm's ability to enter a “dauer” state, which resembles hibernation, may be critical, for example. And shorter-lived species such as worms and fruit flies, whose aging has been delayed the most, may be more susceptible to life-span manipulation. But successful approaches are converging on a few key areas: calorie restriction; reducing levels of insulinlike growth factor 1 (IGF-1), a protein; and preventing oxidative damage to the body's tissues. All three might be interconnected, but so far that hasn't been confirmed (although calorie-restricted animals have low levels of IGF-1).
Just 2 or 3 decades ago, research on aging was a backwater. But when molecular biologists began hunting for ways to prolong life, they found that life span was remarkably pliable. Reducing the activity of an insulinlike receptor more than doubles the life span of worms to a startling—for them—6 weeks. Put certain strains of mice on near-starvation but nutrient-rich diets, and they live 50% longer than normal.
Can these strategies help humans live longer? And how do we determine whether they will? Unlike drugs for cancer or heart disease, the benefits of anti-aging treatments are fuzzier, making studies difficult to set up and to interpret. Safety is uncertain; calorie restriction reduces fertility in animals, and lab flies bred to live long can't compete with their wild counterparts. Furthermore, garnering results—particularly from younger volunteers, who may be likeliest to benefit because they've aged the least—will take so long that by the time results are in, those who began the study will be dead.
That hasn't stopped scientists, some of whom have founded companies, from searching for treatments to slow aging. One intriguing question is whether calorie restriction works in humans. It's being tested in primates, and the National Institute on Aging in Bethesda, Maryland, is funding short-term studies in people. Volunteers in those trials have been on a stringent diet for up to 1 year while researchers monitor their metabolism and other factors that could hint at how they're aging.
Insights could also come from genetic studies of centenarians, who may have inherited long life from their parents. Many scientists believe that average human life span has an inherent upper limit, although they don't agree on whether it's 85 or 100 or 150.
One abiding question in the anti-aging world is what the goal of all this work ought to be. Overwhelmingly, scientists favor treatments that will slow aging and stave off age-related diseases rather than simply extending life at its most decrepit. But even so, slowing aging could have profound social effects, upsetting actuarial tables and retirement plans.
Then there's the issue of fairness: If anti-aging therapies become available, who will receive them? How much will they cost? Individuals may find they can stretch their life spans. But that may be tougher to achieve for whole populations, although many demographers believe that the average life span will continue to climb as it has consistently for decades. If that happens, much of the increase may come from less dramatic strategies, such as heart disease and cancer prevention, that could also make the end of a long life more bearable.


http://www.sciencemag.org/content/309/5731/83.full